Search results for "2803 Biological Psychiatry"

showing 10 items of 11 documents

Association study of a SNP coding for a M129V substitution in the prion protein in schizophrenia.

2003

AdultPsychosisAmyloidAdolescentGenotypePrionsSchizophrenia (object-oriented programming)610 Medicine & healthBiologymedicine.disease_causeGenetic determinismPrion Proteins2738 Psychiatry and Mental HealthOpen Reading FramesPolymorphism (computer science)medicineSNPHumansPoint MutationGenetic Predisposition to DiseaseProtein PrecursorsCodonBiological PsychiatryAgedGeneticsMutationSubstitution (logic)Case-control study11359 Institute for Regenerative Medicine (IREM)Middle Agedmedicine.diseasePsychiatry and Mental healthAmino Acid SubstitutionCase-Control StudiesSchizophrenia2803 Biological PsychiatrySchizophrenia research
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A functional variant of the serotonin transporter gene (SLC6A4) moderates impulsive choice in attention-deficit/hyperactivity disorder boys and sibli…

2011

Item does not contain fulltext BACKGROUND: Impulsive drive for immediate reward (IDIR) and delay aversion are dissociable elements of the preference for immediate over delayed rewards seen in attention-deficit/hyperactivity disorder (ADHD). We hypothesized that IDIR would be associated with dopamine regulating genes and delay aversion would be associated with serotonin-regulating genes. METHODS: Impulsive drive for immediate reward and delay aversion were measured in 459 male children and adolescents (328 ADHD and 131 unaffected siblings) with a laboratory choice task. The sample was genotyped for the 5HTT (SLC6A4) promoter serotonin-transporter-linked polymorphic region polymorphism and a …

DEFICIT HYPERACTIVITY DISORDERMedizinSocial Sciencesimpulsivity610 Medicine & healthCHILDRENSingle-nucleotide polymorphismGenomic disorders and inherited multi-system disorders Functional Neurogenomics [IGMD 3]attention-deficit/hyperactivity disorderImpulsivityCOMBINED-TYPE ADHDREACTION-TIME PERFORMANCEDevelopmental psychologyGenomic disorders and inherited multi-system disorders [IGMD 3]DOPAMINE03 medical and health sciences0302 clinical medicineDopaminemedicineAttention deficit hyperactivity disorderddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAlleleBiological PsychiatrySerotonin transporter030304 developmental biologyDopamine transporterGeneticsMental Health [NCEBP 9]0303 health sciencesDELAY AVERSIONbiologyTRYPTOPHAN DEPLETIONASSOCIATION10058 Department of Child and Adolescent Psychiatrymedicine.diseasePOLYMORPHISM5-HTTLPR (SLC6A4)5-HTTLPRbiology.proteinCRITERION VALIDITYmedicine.symptomDAT1 (SLC6A3)Psychology2803 Biological PsychiatryFunctional Neurogenomics [DCN 2]030217 neurology & neurosurgerymedicine.drugBiological Psychiatry
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Cotransmission of conduct problems with attention-deficit/hyperactivity disorder: familial evidence for a distinct disorder

2008

Contains fulltext : 69215.pdf (Publisher’s version ) (Closed access) Common disorders of childhood and adolescence are attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD) and conduct disorder (CD). For one to two cases in three diagnosed with ADHD the disorders may be comorbid. However, whether comorbid conduct problems (CP) represents a separate disorder or a severe form of ADHD remains controversial. We investigated familial recurrence patterns of the pure or comorbid condition in families with at least two children and one definite case of DSM-IV ADHDct (combined-type) as part of the International Multicentre ADHD Genetics Study (IMAGE). Using case diagno…

MaleNeurologyPsychometricsGenetics and epigenetic pathways of disease [NCMLS 6]MedizinComorbidityNeuroinformatics [DCN 3]Severity of Illness Index2738 Psychiatry and Mental Health0302 clinical medicinePerception and Action [DCN 1]ChildAge Factors10058 Department of Child and Adolescent PsychiatryPsychiatry and Mental health2728 Neurology (clinical)NeurologyConduct disorderFemalePsychology2803 Biological PsychiatryFunctional Neurogenomics [DCN 2]Clinical psychologyConduct Disordermedicine.medical_specialtyAdolescentPsychometrics610 Medicine & healthMental health [NCEBP 9]behavioral disciplines and activitiesGenomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciencesCognitive neurosciences [UMCN 3.2]Severity of illnessmental disordersmedicineAttention deficit hyperactivity disorderHumansddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersPsychiatryBiological PsychiatryFamily HealthReproducibility of Resultsmedicine.diseaseComorbidity030227 psychiatryHyperkinetic disorderGenetic defects of metabolism [UMCN 5.1]Attention Deficit Disorder with HyperactivityRelative risk2808 NeurologyMultivariate AnalysisNeurology (clinical)030217 neurology & neurosurgeryJournal of Neural Transmission
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The Two-Systems Account of Theory of Mind: Testing the Links to Social- Perceptual and Cognitive Abilities

2018

According to the two-systems account of theory of mind (ToM), understanding mental states of others involves both fast social-perceptual processes, as well as slower, reflexive cognitive operations (Frith and Frith, 2008; Apperly and Butterfill, 2009). To test the respective roles of specific abilities in either of these processes we administered 15 experimental procedures to a large sample of 343 participants, testing ability in face recognition and holistic perception, language, and reasoning. ToM was measured by a set of tasks requiring ability to track and to infer complex emotional and mental states of others from faces, eyes, spoken language, and prosody. We used structural equation m…

language10093 Institute of Psychologysocial perceptionlcsh:RC321-5713206 Neuropsychology and Physiological PsychologyBehavioral NeurosciencePsychiatry and Mental health2738 Psychiatry and Mental HealthNeuropsychology and Physiological PsychologyNeurology2808 Neurology2802 Behavioral Neuroscience150 Psychology2803 Biological Psychiatryindividual differenceslcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological Psychiatry10190 Jacobs Center for Productive Youth DevelopmentNeuroscienceOriginal Researchtheory of mindface recognitionFrontiers in Human Neuroscience
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Visual mismatch negativity (vMMN): a prediction error signal in the visual modality

2015

Frontiers in Human Neuroscience, 8

Visual perceptionvisual mismatch negativitySpeech recognitionAutomaticityMismatch negativity610 Medicine & healthStimulus (physiology)Electroencephalographyperceptual learninglcsh:RC321-571170 Ethics3206 Neuropsychology and Physiological Psychology2738 Psychiatry and Mental HealthBehavioral NeuroscienceMMN (Mismatch negativity)Perceptual learning2802 Behavioral Neurosciencemedicine10237 Institute of Biomedical Engineeringstimulus specific adaptationEEGstimulus specific adaptationpredictive codingOddball paradigmlcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological Psychiatryta515prediction errormedicine.diagnostic_testQuantitative Biology::Neurons and CognitionEditorial ArticlePsychiatry and Mental healthNeuropsychology and Physiological PsychologyNeurology2808 NeurologyEEG; ERP; Perceptual Learning; Predictive coding; Prediction error; Repetition suppression; Stimulus specific adaptation; Visual mismatch negativityOblique effectrepetition suppressionPsychology2803 Biological PsychiatryERPCognitive psychologyNeuroscienceFrontiers in Human Neuroscience
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The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperacti…

2008

Contains fulltext : 70708.pdf (Publisher’s version ) (Open Access) ABSTRACT: BACKGROUND: Low serotonergic (5-HT) activity correlates with increased impulsive-aggressive behavior, while the opposite association may apply to cognitive impulsiveness. Both types of impulsivity are associated with attention-deficit/hyperactivity disorder (ADHD), and genes of functional significance for the 5-HT system are implicated in this disorder. Here we demonstrate the separation of aggressive and cognitive components of impulsivity from symptom ratings and test their association with 5-HT and functionally related genes using a family-based association test (FBAT-PC). METHODS: Our sample consisted of 1180 o…

2805 Cognitive Neurosciencemedicine.medical_specialtyNeurologyGenetics and epigenetic pathways of disease [NCMLS 6]Cognitive NeuroscienceMedizin610 Medicine & healthNeuroinformatics [DCN 3]SerotonergicImpulsivityMental health [NCEBP 9]lcsh:RC346-429Genomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineCognitive neurosciences [UMCN 3.2]2802 Behavioral NeurosciencePerception and Action [DCN 1]medicineAttention deficit hyperactivity disorderddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAssociation (psychology)Psychiatrylcsh:Neurology. Diseases of the nervous systemBiological PsychiatryAggressionResearchCognitionGeneral Medicine10058 Department of Child and Adolescent Psychiatrymedicine.disease030227 psychiatryAutism spectrum disordermedicine.symptomPsychologyFunctional Neurogenomics [DCN 2]2803 Biological Psychiatry030217 neurology & neurosurgeryClinical psychology
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Neurochemical alterations in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder

2010

Borderline personality disorder (BPD) is associated with structural and functional brain changes. Recent models and findings refer to alterations of glutamate and total N-acetylaspartate (tNAA) in this condition.Absolute quantities of tNAA, creatine, glutamate, glutamine, myoinositol and total choline were measured using 3 Tesla magnetic resonance spectroscopy of the left anterior cingulate cortex and the left cerebellum in 14 unmedicated women with BPD and comorbid attention-deficit hyperactivity disorder (ADHD) and 18 healthy women. Both groups were matched with respect to age, education and premorbid intelligence.In the anterior cingulate, we found significantly higher tNAA and glutamate…

AdultCerebellummedicine.medical_specialtyMagnetic Resonance SpectroscopyGlutamineGlutamic Acid610 Medicine & health10056 Clinic for Clinical and Social Psychiatry Zurich West (former)CreatineGyrus Cingulibehavioral disciplines and activitiesCholine2738 Psychiatry and Mental Healthchemistry.chemical_compoundGlutamatergicNeurochemicalBorderline Personality DisorderCerebellumInternal medicinemental disordersmedicineHumansAttention deficit hyperactivity disorderBorderline personality disorderBiological PsychiatryBrain ChemistryAspartic AcidGlutamate receptorCreatinemedicine.diseaseGlutaminePsychiatry and Mental healthmedicine.anatomical_structureEndocrinologychemistryAttention Deficit Disorder with HyperactivityCase-Control StudiesPsychology2803 Biological PsychiatryInositolClinical psychologyThe World Journal of Biological Psychiatry
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Factors associated with non-treatment or delayed treatment seeking in OCD sufferers: a review of the literature.

2013

Obsessive-compulsive disorder (OCD) is a disabling disorder that can be successfully treated. However, a high percentage of sufferers neither ask for nor receive treatment for their symptoms, or they delay seeking treatment. The factors underlying the treatment-seeking behaviour of OCD patients are still not clear. This review includes 12 studies published before April 2014 that analyse the possible variables related to the delayed help-seeking behaviour of OCD patients. Studies showed that individuals who asked for help were more impaired and reported poorer quality of life. Help-seeking behaviour was associated with greater insight, severity, specific obsessive-compulsive symptoms, such a…

Financial costsmedicine.medical_specialtyObsessive-Compulsive Disordermedia_common.quotation_subjectShame610 Medicine & healthHelp seeking behavior2738 Psychiatry and Mental HealthQuality of life (healthcare)mental disordersmedicineHumansHealth care seekingPsychiatryBiological Psychiatrymedia_commonDelayed treatmentPatient Acceptance of Health Caremedicine.diseaseMental healthComorbidityPsychiatry and Mental health10057 Klinik für Konsiliarpsychiatrie und PsychosomatikPsychology2803 Biological PsychiatryClinical psychologyPsychiatry research
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Linkage to chromosome 1p36 for attention-deficit/hyperactivity disorder traits in school and home settings.

2008

Contains fulltext : 69485.pdf (Publisher’s version ) (Closed access) BACKGROUND: Limited success has been achieved through previous attention-deficit/hyperactivity disorder (ADHD) linkage scans, which were all designed to map genes underlying the dichotomous phenotype. The International Multi-centre ADHD Genetics (IMAGE) project performed a whole genome linkage scan specifically designed to map ADHD quantitative trait loci (QTL). METHODS: A set of 1094 single selected Caucasian ADHD nuclear families was genotyped on a highly accurate and informative single nucleotide polymorphism (SNP) panel. Two quantitative traits measuring the children's symptoms in home and school settings were collecte…

MaleAdolescentGenetics and epigenetic pathways of disease [NCMLS 6]Genetic LinkageMedizin610 Medicine & healthSingle-nucleotide polymorphismLocus (genetics)Quantitative trait locusNeuroinformatics [DCN 3]Social EnvironmentMental health [NCEBP 9]ArticleWhite PeopleDyslexiaGenomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciences0302 clinical medicineCognitive neurosciences [UMCN 3.2]Genetic linkagemental disordersmedicinePerception and Action [DCN 1]HumansAttention deficit hyperactivity disorderddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersChildBiological PsychiatryGenetics0303 health sciencesSchools030305 genetics & heredityDyslexia10058 Department of Child and Adolescent PsychiatryHeritabilitymedicine.disease030227 psychiatryPhenotypeGenetic defects of metabolism [UMCN 5.1]Attention Deficit Disorder with HyperactivityChromosomes Human Pair 1Child PreschoolTraitFemalePsychology2803 Biological PsychiatryFunctional Neurogenomics [DCN 2]
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Depression during an acute episode of schizophrenia or schizophreniform disorder and its impact on treatment response

2008

The aim of the present study was to examine the relevance of depressive symptoms during an acute schizophrenic episode for the prediction of treatment response. Two hundred inpatients who fulfilled DSM-IV criteria for schizophrenia or schizophreniform disorders were assessed at hospital admission and after 6 weeks of inpatient treatment using the Positive and Negative Syndrome Scale (PANSS) and the Hamilton Rating Scale for Depression (HAM-D). Depressive symptoms showed positive correlations with both positive and negative symptoms at admission and after 6 weeks, and decreased during 6 weeks of treatment. Pronounced depressive symptoms (HAM-D score> or =16) were found in 28% of the sample a…

AdultMalemedicine.medical_specialtyPsychosis610 Medicine & healthComorbidity10056 Clinic for Clinical and Social Psychiatry Zurich West (former)law.invention2738 Psychiatry and Mental Health03 medical and health sciencesPatient Admission0302 clinical medicineRandomized controlled triallawInternal medicinemental disordersmedicineHumansSchizophreniform disorderPsychiatryBiological PsychiatryDepression (differential diagnoses)ProbabilityPsychiatric Status Rating ScalesDepressive DisorderDepressive Disorder MajorPsychotropic DrugsPositive and Negative Syndrome ScaleHamilton Rating Scale for Depressionmedicine.diseaseComorbidity030227 psychiatryDiagnostic and Statistical Manual of Mental DisordersHospitalizationPsychiatry and Mental healthTreatment OutcomePsychotic DisordersSchizophreniaAcute DiseaseSchizophreniaFemaleSchizophrenic PsychologyPsychology2803 Biological Psychiatry030217 neurology & neurosurgeryAntipsychotic AgentsFollow-Up Studies
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